Http error & new submissions, installed plugins not loading

I am facing issue that new user not creating now. Secondly if existing user are submitting the submission it is not saving. Thirdly installed plugins are not loading. Forth when reviewer upload fil, it’s display HTTP ERROR. In all scenarios loading circle rotating but function are not performing.

I found these errors in error_log file

PHP Fatal error: Uncaught PDOException: SQLSTATE[23000]: Integrity constraint violation: 1062 Duplicate entry ‘c5cfbd770efabb087829cdbc64a8af57’ for key ‘sessions_pkey’ in /home/afxvwsmy/public_html/lib/pkp/lib/vendor/doctrine/dbal/lib/Doctrine/DBAL/Driver/PDOStatement.php:115
Stack trace:
#0 /home/afxvwsmy/public_html/lib/pkp/lib/vendor/doctrine/dbal/lib/Doctrine/DBAL/Driver/PDOStatement.php(115): PDOStatement->execute(NULL)
#1 /home/afxvwsmy/public_html/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(489): Doctrine\DBAL\Driver\PDOStatement->execute()
#2 /home/afxvwsmy/public_html/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(664): Illuminate\Database\Connection->Illuminate\Database{closure}(‘INSERT INTO ses…’, Array)
#3 /home/afxvwsmy/public_html/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(631): Illuminate\Database\Connection->runQueryCallback(‘INSERT INTO ses…’, Array, Object(Closure))
#4 /home/afxvwsmy/public_html/lib/pkp/lib/ve in /home/afxvwsmy/public_html/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php on line 671
[29-Oct-2025 03:15:06 UTC] PHP Deprecated: Non-static method PKPApplication::getRequest() should not be called statically in /home/afxvwsmy/public_html/plugins/themes/default/DefaultThemePlugin.inc.php on line 135

PHP Fatal error: Uncaught Error: Call to a member function getId() on null in /home/afxvwsmy/public_html/pages/issue/IssueHandler.inc.php:52
Stack trace:
#0 /home/afxvwsmy/public_html/lib/pkp/classes/core/PKPRouter.inc.php(392): IssueHandler->initialize(Object(Request), Array)
#1 /home/afxvwsmy/public_html/lib/pkp/classes/core/PKPPageRouter.inc.php(246): PKPRouter->_authorizeInitializeAndCallRequest(Array, Object(Request), Array, false)
#2 /home/afxvwsmy/public_html/lib/pkp/classes/core/Dispatcher.inc.php(144): PKPPageRouter->route(Object(Request))
#3 /home/afxvwsmy/public_html/lib/pkp/classes/core/PKPApplication.inc.php(362): Dispatcher->dispatch(Object(Request))
#4 /home/afxvwsmy/public_html/home.php(69): PKPApplication->execute()
#5 /home/afxvwsmy/public_html/index.php(37): include(‘/home/afxvwsmy/…’)
#6 {main}
thrown in /home/afxvwsmy/public_html/pages/issue/IssueHandler.inc.php on line 52

PHP Fatal error: Uncaught Error: Call to a member function getId() on null in /home/afxvwsmy/public_html/pages/issue/IssueHandler.inc.php:52
Stack trace:
#0 /home/afxvwsmy/public_html/lib/pkp/classes/core/PKPRouter.inc.php(392): IssueHandler->initialize(Object(Request), Array)
#1 /home/afxvwsmy/public_html/lib/pkp/classes/core/PKPPageRouter.inc.php(246): PKPRouter->_authorizeInitializeAndCallRequest(Array, Object(Request), Array, false)
#2 /home/afxvwsmy/public_html/lib/pkp/classes/core/Dispatcher.inc.php(144): PKPPageRouter->route(Object(Request))
#3 /home/afxvwsmy/public_html/lib/pkp/classes/core/PKPApplication.inc.php(362): Dispatcher->dispatch(Object(Request))
#4 /home/afxvwsmy/public_html/home.php(69): PKPApplication->execute()
#5 /home/afxvwsmy/public_html/index.php(37): include(‘/home/afxvwsmy/…’)
#6 {main}
thrown in /home/afxvwsmy/public_html/pages/issue/IssueHandler.inc.php on line 52

PHP Fatal error: Uncaught PDOException: SQLSTATE[HY000]: General error: 1116 Too many tables; MySQL can only use 61 tables in a join in /home/afxvwsmy/public_html/lib/pkp/lib/vendor/doctrine/dbal/lib/Doctrine/DBAL/Driver/PDOConnection.php:78
Stack trace:
#0 /home/afxvwsmy/public_html/lib/pkp/lib/vendor/doctrine/dbal/lib/Doctrine/DBAL/Driver/PDOConnection.php(78): PDO->prepare(‘SELECT\n\t\t\t\to.su…’, Array)
#1 /home/afxvwsmy/public_html/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(361): Doctrine\DBAL\Driver\PDOConnection->prepare(Object(Illuminate\Database\Query\Expression))
#2 /home/afxvwsmy/public_html/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(664): Illuminate\Database\Connection->Illuminate\Database{closure}(Object(Illuminate\Database\Query\Expression), Array)
#3 /home/afxvwsmy/public_html/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(631): Illuminate\Database\Connection->runQueryCallback(Object(Illuminate\Database\Query\Expre in /home/afxvwsmy/public_html/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php on line 671

PHP Fatal error: Uncaught PDOException: SQLSTATE[23000]: Integrity constraint violation: 1062 Duplicate entry ‘c5cfbd770efabb087829cdbc64a8af57’ for key ‘sessions_pkey’ in /home/afxvwsmy/public_html/lib/pkp/lib/vendor/doctrine/dbal/lib/Doctrine/DBAL/Driver/PDOStatement.php:115
Stack trace:
#0 /home/afxvwsmy/public_html/lib/pkp/lib/vendor/doctrine/dbal/lib/Doctrine/DBAL/Driver/PDOStatement.php(115): PDOStatement->execute(NULL)
#1 /home/afxvwsmy/public_html/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(489): Doctrine\DBAL\Driver\PDOStatement->execute()
#2 /home/afxvwsmy/public_html/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(664): Illuminate\Database\Connection->Illuminate\Database{closure}(‘INSERT INTO ses…’, Array)
#3 /home/afxvwsmy/public_html/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php(631): Illuminate\Database\Connection->runQueryCallback(‘INSERT INTO ses…’, Array, Object(Closure))
#4 /home/afxvwsmy/public_html/lib/pkp/lib/ve in /home/afxvwsmy/public_html/lib/pkp/lib/vendor/laravel/framework/src/Illuminate/Database/Connection.php on line 671

What application are you using?
For example, OJS 3.3.0-6

Additional information
Admin and login site for submission is not working properly. Installed Plugins also not loading. Loading circle is spinning but not loading. New login also not creating and user submission is also not working properly. Please help and guide.

@asmecher Please guide for this issue