HTTP error during upload of submission file OMP 3.1.1.4

I got “HTTP error” during upload of submission file OMP 3.1.1.4 (it run on Ubuntu 14.04)
Greatly appreciated, if some one can guide me to resolve this problem. The PHP log is as follows.
[Mon Oct 22 13:15:57.235160 2018] [:error] [pid 1081] [client 74.83.196.174:53784] PHP Warning: mkdir(): Permission denied in /abcd/omp/lib/pkp/classes/file/FileManager.inc.php on line 289, referer: http://www.sci-en-tech.com/Books/index.php/eBooks/submission/wizard/2?submissionId=38
[Mon Oct 22 13:15:57.235258 2018] [:error] [pid 1081] [client 74.83.196.174:53784] PHP Warning: move_uploaded_file(/xyz/omp2/presses/1//monographs/38/submission/38-2-125-1-2-20181022.doc): failed to open stream: No such file or directory in /abcd/omp/lib/pkp/classes/file/FileManager.inc.php on line 119, referer: http://www.sci-en-tech.com/Books/index.php/eBooks/submission/wizard/2?submissionId=38
[Mon Oct 22 13:15:57.235274 2018] [:error] [pid 1081] [client 74.83.196.174:53784] PHP Warning: move_uploaded_file(): Unable to move ‘/tmp/phpXexDQM’ to ‘/xyz/omp2/presses/1//monographs/38/submission/38-2-125-1-2-20181022.doc’ in /abcd/omp/lib/pkp/classes/file/FileManager.inc.php on line 119, referer: http://www.sci-en-tech.com/Books/index.php/eBooks/submission/wizard/2?submissionId=38
[Mon Oct 22 13:15:57.237429 2018] [:error] [pid 1081] [client 74.83.196.174:53784] PHP Fatal error: Call to a member function getFileId() on a non-object in /abcd/omp/lib/pkp/classes/submission/PKPSubmissionFileDAO.inc.php on line 1065, referer: http://www.sci-en-tech.com/Books/index.php/eBooks/submission/wizard/2?submissionId=38