In short, OJS 3.3.0-x used en_US as a locale code for English, and starting with 3.4.0-x, we use en instead. However, your database seems to already contain some data with the en locale code. Did you attempt an upgrade that failed? If so, you’ll need to restore from backup to a “clean” 3.3.0-x database.
Regards,
Alec Smecher
Public Knowledge Project Team